Scientific interest with a focus on cell biology
My research interest in the biological sciences ties on the application and extension of our knowledge today of the mechanisms underlying the complexity of biological phenomena as well as to investigate on the advancement of our understanding of the miracle of life.
Especially the dynamic organization of life, including many cellular processes (such as protein and gene regulation), the versatile architecture of cells or patterns of cellular communication, is what fascinates me most. In particular how biological processes can be guided spatially and temporally and how highly regulated mechanisms are established on a molecular basis.
To highlight a few:
Functional Genomics and Signalling Biochemistry (characterization of gene fct. and cellular signaling pathways, especially in terms of defects at different levels of expression and the gene or pathway interaction networks (feedback loops, cross-talk, etc.). Connectively gene regulation (herewith particularly on the RNA level).
Furtheron protein regulation (post-transcriptional modification, conformational changes, protein-protein interactions and/or complex formation; in particular the connection between the structure and functionality of proteins effecting their spectrum of interaction).
Membrane and protein traffic (systems of vesicle transport, targeting of cargo, exo- and endocytosis, organization of budding and docking sites).
From an immunobiology standpoint: The mechanisms of action of different pathogens, the metabolism of toxins, and physiological strategies against intruders and/or xenobiotics.
And my latest field of interest: Epigenetics.
back to the biosciences front page / zurück zur Biowissenschaft Titelseite
back to front page / zurück zur Titelseite